Acetylcholinesterase inhibition by flavonoids from Agrimonia pilosa.
نویسندگان
چکیده
In a bioassay-guided search for acetylcholinesterase (AChE) inhibitors from 180 medicinal plants, an ethyl acetate extract of whole plants of Agrimonia pilosa ledeb yielded tiliroside (1), 3-methoxy quercetin (2), quercitrin (3) and quercetin (4). We report herein for the first time that all four flavonol compounds showed significant inhibitory effects on AChE, particularly quercetin (4), which showed twice the activity of dehydroevodiamine (DHED).
منابع مشابه
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ورودعنوان ژورنال:
- Molecules
دوره 12 9 شماره
صفحات -
تاریخ انتشار 2007